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Staining (Fig. 2A, lane 3). LP11 reactivity is considered to be a critical test of gH-gL conformation, since this MAb reacts with gH only when it is part of the native complex (29). Second, LP11 neutralizes virus infectivity at high titers and therefore recognizes an immunologically important epitope (4). Purified gHt-gL was immuno-FIG. 2. Extracellular expression and purification of gHt-gL comple

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