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FLCN helps bring about your peri-nuclear clustering involving lysosomes pursuing solution and also amino acid revulsion and it is backed up by your primarily Golgi-associated modest GTPase Rab34. Rab34-positive peri-nuclear membranes make contact with lysosomes as well as cause a lowering of lysosome mobility and knockdown regarding FLCN stops Rab34-induced peri-nuclear lysosome clustering. FLCN i

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