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Tochondrial Diabetes: Molecular Mechanisms and Clinical Presentation. Diabetes 2004, 53:S103-S109. 35. Tarsio JF, Reger LA, Furcht LT: Molecular mechanisms in basement membrane complications of diabetes. Alterations in heparin, laminin, and type IV collagen association. Diabetes 1988, 37:532-539. 36. Bioconductor. [http://www.bioconductor.org]. 37. Ashburner M, Ball CA, Blake JA, Botstein D, Butl