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Eption whether the vector administration occurred at 2 weeks or 6 weeks following injury (p > 0.05 for all behavioral tests). The only difference was detected at 5 weeks post injection for mechanical hyperalgesia, when animals injected at 2 weeks post SCI showed significantly higher sensitivity to mechanical pressure than animals injected at 6 weeks (p

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Remainder of the study (7 weeks) and could be transiently reversed by intrathecal administration of anti-serine histogranin antibody and theopiate antagonist naloxone, suggesting the participation of opioid and NMDA receptors in the observed effects. Gene therapy has several benefits compared to traditional pharmacological therapy. The use of viral vectors offers a potential therapeutic option fo